Clinical Microbiology and Yeast Congress

Yeast-Based Drug Discovery

The humanized yeast model has emerged as a powerful tool in large-scale screenings directed to target human proteins. The high degree of cellular processes conservation between the yeast Saccharomyces cerevisiae and higher eukaryotes has made this microorganism a valuable cell model to study the pathobiology of several human diseases.  The yeast target-based approach can be highly useful in the first-line screening of potentially active compounds to be tested in more complex cell models.