Biography
Cooper investigated avian oil droplets as an undergraduate, obtained an M.S. in Chemistry studying carboxylase enzyme mechanisms at Wayne State and a Ph.D. at Purdue first discovering that ?-oxidation occurs in peroxisomes rather than mitochondria. With Magasanik at MIT he investigated the mechanism of carbon catabolite repression in E. coli. While there he and Patricia Whitney discovered yeast urea amidolyase to be a multifunctional protein consisting of urea carboxylase and allophanate hydrolase. Moving to the University of Pittsburgh, he and his students elucidated the reactions of the allantoin degradative pathway, proposed nitrogen catabolite repression (NCR) as controlling nitrogen-responsive gene expression and he authored “The Tools of Biochemistryâ€. Cooper learned the intricacies of yeast genetics from Sye Fogel and cloning from John Carbon. His group identified, mapped, cloned and sequenced the allantoin pathway structural and four GATA-transcriptional regulatory genes. As Harriet S. Van Vleet Professor at the University of Tennessee, he founded and directed the Molecular Resource Center and was chair of Microbiology and Immunology for 15 years. His students identified the promoter structures of the NCR-sensitive genes, binding sites for their four regulatory transcription factors and now the regulatory pathways controlling Gln3 localization and intra-nuclear regulation. He served 17 years on and chaired NIH and ACS study sections, chaired the AAMC Council of Academic Societies, served on the AAMC Executive Committee, multiple editorial boards and as treasurer and American representative to the International Conference of Yeast Genetics and Molecular Biology. He is currently a member of the UT Board of Trustees.
Research Interest
Yeast,Microbiology, Immunology, and Biochemistry
Biography
Dr.Jürgen Wendland, PhD He is currently Editor-in-Chief, Microbiological Research Beverage Science and Food Safety, Institute of Microbiology and Biochemistry, Geisenheim University, Von-Lade-Str. 1, 65366, Geisenheim, Germany Study of Biology at the Justus-Liebig University (1987-1993), Giessen, Germany. PhD in Genetics, in 1996 Philipps University Marburg, Germany Postdoc at the Biozentrum (1996-1999), University of Basel, Switzerland with Peter Philippsen. He is Group leader at the Friedrich-Schiller University and the Hans-Knöll Institute (2000-2006), Jena, Germany Professor of Yeast Biology and Fermentation at The Carlsberg Laboratory (2006-2016), Copenhagen, Denmark Professor of Microbiology at the Vrije Universiteit Brussel (2016-2019), Brussels, Belgium Since 2019 Professor and Director of the Institute of Microbiology and Biochemistry, Hochschule Geisenheim University, Geisenheim, Germany.
Research Interest
Research focuses on Wine Microbiology and Wine Aroma Analytics. Molecular Yeast Breeding and Yeast Genomics. Wine/Beer and Non-conventional Yeasts Synthetic biology and Genetic Engineering.
Biography
Monique Bolotin-Fukuhara completed her Ph.D. in 1977 at University Paris-Sud-Orsay and worked as an assistant-professor in Genetics at the University of Paris up to 1984. She then entered the Centre National de la Recherche Scientifique as Director of Research. During this period she went twice to the United States (in Chicago -Prs Esposito- and Madison- Pr M. Nomura) for training or sabbatical. From 2006 to 2010, she was Director of the Institute of Genetics and Microbiology at Orsay. She has served on different scientific committees such as the Science Academy of Finland or Scientific board of Institut de la Recherche Agronomique. She was editor of Yeast for many years and is now editor of FEMS Yeast Research while reviewing for many Journals. She has published about one hundred publications in international journals. She is now an Emeritus Research Director of CNRS.
Research Interest
yeasts mitochondrial genetics - Use yeast for mitochondrial diseases, in particular, to search for correcting genes