Cellular Aging

Aging is not typically measured by time in yeast, but rather by the number of divisions an individual cell completes before it dies. An individual cell is easy to follow from birth to death because yeast divides asymmetrically by budding off new daughters. Unlike their mothers, the daughters start from scratch, having the potential for a full life span. Thus, individual cells are mortal, while the yeast population is immortal. The probability that a cell will continue dividing decreases exponentially as a function of the number of completed divisions. Thus, mortality rate increases exponentially with age. However, it plateaus at older ages in similarity to what has been observed in other species. Yeasts undergo a variety of changes as they age, and some of these are clearly detrimental. In view of this, it is reasonable to speak of an aging process. In practical terms, yeast life span is measured by observing individual cells periodically under a microscope and removing buds with a micro-manipulator.

  • Systems-based model of cell death and ageing processes
  • Metabolic regulation of cell stress response

Related Conferences

28th International Conference on Yeast Genetics and Molecular Biology (ICYGMB) August 27 – September 1, 2017 Prague, Czech Republic; The Ageing Cell Conference 2017, March 27-28, UK; Pharmaceutical Microbiology USA 08-09 Jun 2017,San Diego, United States; 28th International Conference on Yeast Genetics and Molecular Biology (ICYGMB) August 27 – September 1, 2017, Prague, Czech Republic; Cellular & Molecular Fungal Biology Gordon Research Conference June 19-24, 2016, Holderness School Holderness, NH; Comparative biology of aging, October 12-16, 2015,Roscoff (Brittany), France; PYFF6 - 6th Conference on Physiology of Yeasts and Filamentous Fungi, July 11-14, 2016, Lisbon, Portugal

Related Associations

  • Biotechnology Industry Association
  • The Society for Pharmaceutical and Biotech Trainers
  • Society for Industrial Microbiology and Biotechnology (SIMB)
  • American Society for Microbiology
  • Australian Biotechnology Association
  • Biotechnology and Biological Research Council
  • Federation of European Microbiological Societies

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